FEATURES

FAMILY

DESCRIPTION

Also known as TKN4_HUMAN, TAC4. Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TAC4

Tachykinin-4

TAC4

Molecular Synopsis