FEATURES

DESCRIPTION

Also known as CAPS2_HUMAN, CADPS2, CAPS2, KIAA1591. Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). Homodimer (By similarity). Interacts with the dopamine receptor DRD2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CADPS2

Calcium-dependent secretion activator 2

CADPS2

Molecular Synopsis