FEATURES

FAMILY

DESCRIPTION

Also known as HPLN4_HUMAN, HAPLN4, BRAL2, KIAA1926. Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs (By similarity). Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HAPLN4

Hyaluronan and proteoglycan link protein 4

HAPLN4

Molecular Synopsis