FEATURES

FAMILY

DESCRIPTION

Also known as PIGZ_HUMAN, PIGZ, SMP3. Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PIGZ

GPI mannosyltransferase 4

PIGZ

Molecular Synopsis