FEATURES

FAMILY

DESCRIPTION

Also known as DAAF5_HUMAN, DNAAF5, HEATR2. Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility. Interacts with DNAI2; probably involved in outer arm dynein assembly.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DNAAF5

Dynein axonemal assembly factor 5

DNAAF5

Molecular Synopsis