FEATURES

FAMILY

DESCRIPTION

Also known as DLP1_HUMAN, PDSS2, C6orf210, DLP1. Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone (PubMed:16262699). Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively (PubMed:16262699). The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry (PubMed:16262699). May play a role during cerebellar development (By similarity). May regulate mitochondrial respiratory chain function (By similarity). Heterotetramer composed of 2 PDSS1/DPS1 and 2 PDSS2/DLP1 subunits.

Also known as DLP1_HUMAN, PDSS2, C6orf210, DLP1. Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) t ...

EXTERNAL LINKS

PDSS2

All trans-polyprenyl-diphosphate synthase PDSS2

PDSS2

Molecular Synopsis