FEATURES

FAMILY

DESCRIPTION

Also known as RHPN2_HUMAN, RHPN2. Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. Interacts with GTP-bound RhoA and RhoB. Interacts with both GTP- and GDP-bound RhoA. According to PubMed:12473120, it does not interact with RhoA. Interacts with KRT18.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RHPN2

Rhophilin-2

RHPN2

Molecular Synopsis