FEATURES

FAMILY

DESCRIPTION

Also known as MY18B_HUMAN, MYO18B. May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth. Homodimer. May interact with F actin through the GPA motif (Gly/Pro/Ala-rich).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MYO18B

Unconventional myosin-XVIIIb

MYO18B

Molecular Synopsis