FEATURES

FAMILY

DESCRIPTION

Also known as VRK3_HUMAN, VRK3. Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus. Interacts with DUSP3 (By similarity). Interacts with RAN.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

VRK3

Inactive serine/threonine-protein kinase VRK3

VRK3

Molecular Synopsis