FEATURES

DESCRIPTION

Also known as PKHH2_HUMAN, PLEKHH2, KIAA2028. In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia. Self-associates. Interacts with TGFB1I1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PLEKHH2

Pleckstrin homology domain-containing family H member 2

PLEKHH2

Molecular Synopsis