FEATURES

FAMILY

DESCRIPTION

Also known as NNRD_HUMAN, NAXD, CARKD. Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NAXD

ATP-dependent (S)-NAD(P)H-hydrate dehydratase

NAXD

Molecular Synopsis