FEATURES

FAMILY

DESCRIPTION

Also known as ANKH1_HUMAN, ANKHD1, KIAA1085, MASK, VBARP. May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR. Interacts with NOD2 (PubMed:27812135).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ANKHD1

Ankyrin repeat and KH domain-containing protein 1

ANKHD1

Molecular Synopsis