FEATURES

FAMILY

DESCRIPTION

Also known as DRC7_HUMAN, DRC7, C16orf50, CCDC135. Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Involved in the regulation of flagellar motility (By similarity). Essential for male fertility, sperm head morphogenesis and sperm flagellum formation (By similarity). Component of the nexin-dynein regulatory complex (N-DRC). Interacts with TCTE1/DRC5 (By similarity). Interacts with DRC3 and GAS8/DRC4 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DRC7

Dynein regulatory complex subunit 7

DRC7

Molecular Synopsis