FEATURES

DESCRIPTION

Also known as DND1_HUMAN, DND1, RBMS4. RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity). Interacts with APOBEC3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DND1

Dead end protein homolog 1

DND1

Molecular Synopsis