FEATURES

FAMILY

DESCRIPTION

Also known as TM86A_HUMAN, TMEM86A. Catalyzes the hydrolysis of the vinyl ether bond of choline or ethanolamine lysoplasmalogens, forming fatty aldehyde and glycerophosphocholine or glycerophosphoethanolamine, respectively and is specific for the sn-2-deacylated (lyso) form of plasmalogen (PubMed:36592658). Plays an important role in lysoplasmalogen metabolism in the adipocyte tissue and macrophages (PubMed:36592658).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TMEM86A

Lysoplasmalogenase TMEM86A

TMEM86A

Molecular Synopsis