FEATURES

DESCRIPTION

Also known as MCPH1_HUMAN, MCPH1. Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex. Interacts with CDC27 and maybe other components of the APC/C complex. Interacts with histone variant H2AX under DNA damage conditions.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MCPH1

Microcephalin

MCPH1

Molecular Synopsis