FEATURES

FAMILY

DESCRIPTION

Also known as CHSTD_HUMAN, CHST13. Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1, 4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CHST13

Carbohydrate sulfotransferase 13

CHST13

Molecular Synopsis