FEATURES

DESCRIPTION

Also known as MYRIP_HUMAN, MYRIP, SLAC2C. Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity). Binds MYO5A, MYO7A and F-actin (By similarity). Binds RAB27A that has been activated by GTP-binding via its N-terminus. Interacts with PRKAR2A. Interacts with components of the exocyst complex, including EXOC3 and EXOC4 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MYRIP

Rab effector MyRIP

MYRIP

Molecular Synopsis