FEATURES

FAMILY

DESCRIPTION

Also known as NT5C_HUMAN, NT5C, DNT1, UMPH2. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. Homodimer.

Also known as NT5C_HUMAN, NT5C, DNT1, UMPH2. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and l ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NT5C

5'(3')-deoxyribonucleotidase, cytosolic type

NT5C

Molecular Synopsis