FEATURES

FAMILY

DESCRIPTION

Also known as ELP5_HUMAN, ELP5, C17orf81, DERP6. Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). Involved in cell migration (By similarity). Component of the elongator complex which consists of ELP1, ELP2, ELP3, ELP4, ELP5 and ELP6; in the complex, is required for optimal binding of ELP3 to ELP4.

Also known as ELP5_HUMAN, ELP5, C17orf81, DERP6. Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U ( ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ELP5

Elongator complex protein 5

ELP5

Molecular Synopsis