FEATURES

FAMILY

DESCRIPTION

Also known as GLYL2_HUMAN, GLYATL2. Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine (PubMed:22475485, PubMed:20305126). Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine (PubMed:20305126).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GLYATL2

Glycine N-acyltransferase-like protein 2

GLYATL2

Molecular Synopsis