FEATURES

FAMILY

DESCRIPTION

Also known as KCNE4_HUMAN, KCNE4. Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current. Interacts with KCNQ1; impairs KCNQ1 localization in lipid rafts and inhibits voltage-gated potassium channel activity.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KCNE4

Potassium voltage-gated channel subfamily E member 4

KCNE4

Molecular Synopsis