FEATURES

FAMILY

DESCRIPTION

Also known as ASB12_HUMAN, ASB12. Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Interacts with CUL5 and RNF7.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ASB12

Ankyrin repeat and SOCS box protein 12

ASB12

Molecular Synopsis