FEATURES

FAMILY

DESCRIPTION

Also known as NANO1_HUMAN, NANOS1, NOS1. May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. Interacts with PUM2, SNAPIN and CTNNB1. Interacts (via N-terminal region) with CTNND1. Interacts with DDX20 (via N-terminal region).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NANOS1

Nanos homolog 1

NANOS1

Molecular Synopsis