FEATURES

FAMILY

sodium:solute symporter (SSF) (TC 2.A.21) family

DESCRIPTION

Also known as SC5A5_HUMAN, SLC5A5, NIS. Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:8806637, PubMed:9329364, PubMed:20797386, PubMed:12488351, PubMed:18372236, PubMed:18708479, PubMed:31310151, PubMed:32084174). Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:12488351). Homodimer; disulfide-linked (PubMed:20797386, PubMed:18372236, PubMed:31310151). Monomer (PubMed:20797386, PubMed:18372236, PubMed:31310151). Homooligomer (PubMed:20797386, PubMed:18372236, PubMed:31310151).

Also known as SC5A5_HUMAN, SLC5A5, NIS. Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:8806637, PubMed:9329364, PubMed:20797386, PubMed:12488351, Pu ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC5A5

Sodium/iodide cotransporter

SLC5A5

Molecular Synopsis