FEATURES

FAMILY

DESCRIPTION

Also known as EXTL1_HUMAN, EXTL1, EXTL. Glycosyltransferase required for the biosynthesis of heparan-sulfate (HS) (PubMed:11390981). Transfers N-acetyl-alpha-D-glucosamine to the nascent HS chain (GlcNAcT-II activity) (PubMed:11390981). Appears to lack GlcNAcT I and GlcAT-II activities (PubMed:11390981).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EXTL1

Exostosin-like 1

EXTL1

Molecular Synopsis