FEATURES

DESCRIPTION

Also known as PRG4_HUMAN, PRG4, MSF, SZP. Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface., Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages. Homodimer; disulfide-linked.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PRG4

Proteoglycan 4

PRG4

Molecular Synopsis