FEATURES

FAMILY

DESCRIPTION

Also known as MID49_HUMAN, MIEF2, MID49, SMCR7. Mitochondrial outer membrane protein involved in the regulation of mitochondrial organization (PubMed:29361167). It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity. Interacts with DNM1L.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MIEF2

Mitochondrial dynamics protein MID49

MIEF2

Molecular Synopsis