FEATURES

DESCRIPTION

Also known as ERLEC_HUMAN, ERLEC1, C2orf30, XTP3TPB. Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins. May form a complex with OS9, HSPA5, SYVN1, and SEL1L with which it interacts directly. Interacts (via PRKCSH 2 domain) with KREMEN2 (when glycosylated). Interacts with HSPA5.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ERLEC1

Endoplasmic reticulum lectin 1

ERLEC1

Molecular Synopsis