FEATURES

FAMILY

small G protein signaling modulator family

DESCRIPTION

Also known as SGSM3_HUMAN, SGSM3, MAP, RABGAPLP, RUTBC3. May play a cooperative role in NF2-mediated growth suppression of cells. Interacts with GJA1. Interaction with GJA1 induces its degradation (By similarity). Interacts via its RUN domain with the C-terminal region of NF2. Interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A, RAP2B and PDCD6IP. No interaction with RAB27A.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SGSM3

Small G protein signaling modulator 3

SGSM3

Molecular Synopsis