FEATURES

FAMILY

DESCRIPTION

Also known as DYH8_HUMAN, DNAH8. Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Consists of at least two heavy chains and a number of intermediate and light chains.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DNAH8

Dynein axonemal heavy chain 8

DNAH8

Molecular Synopsis