FEATURES

FAMILY

DESCRIPTION

Also known as EXOC2_HUMAN, EXOC2, SEC5, SEC5L1. Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with EXOC3L1 (By similarity). Interacts with GNEFR/DELGEF; this interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP (PubMed:12459492). Interacts with RALA and RALB (PubMed:18756269, PubMed:19166349, PubMed:12459492) (By similarity). Interacts with ARL13B; regulates ARL13B localization to the cilium membrane.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EXOC2

Exocyst complex component 2

EXOC2

Molecular Synopsis