FEATURES

FAMILY

short-chain dehydrogenases/reductases (SDR) family

DESCRIPTION

Also known as DHRS1_HUMAN, DHRS1, SDR19C1. NADPH-dependent oxidoreductase which catalyzes the reduction of steroids (estrone, androstene-3, 17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro (PubMed:30031147). May have a role in steroid and/or xenobiotic metabolism (PubMed:30031147).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DHRS1

Dehydrogenase/reductase SDR family member 1

DHRS1

Molecular Synopsis