FEATURES

DESCRIPTION

Also known as LRGUK_HUMAN, LRGUK. Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. Interacts (via guanylate kinase-like domain) with RIMBP3 (via coiled-coil region). Interacts (via guanylate kinase-like domain) with HOOK2. Interacts (via LRRCT domain) with KLC3. Interacts with HOOK1 and HOOK3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LRGUK

Leucine-rich repeat and guanylate kinase domain-containing protein

LRGUK

Molecular Synopsis