FEATURES

FAMILY

DESCRIPTION

Also known as MND1_HUMAN, MND1, GAJ. Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MND1

Meiotic nuclear division protein 1 homolog

MND1

Molecular Synopsis