FEATURES

FAMILY

DESCRIPTION

Also known as LT4R2_HUMAN, LTB4R2, BLT2R, BLTR2. Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LTB4R2

Leukotriene B4 receptor 2

LTB4R2

Molecular Synopsis