FEATURES

FAMILY

DESCRIPTION

Also known as PPME1_HUMAN, PPME1, PME1. Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. Binds PPP2CA and PPP2CB.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PPME1

Protein phosphatase methylesterase 1

PPME1

Molecular Synopsis