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canSAR.ai Protein Annotation Tool

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Add Genes to the report

Enter gene list (max 1000) separated by commas, new lines, spaces or tabs.

Formats accepted are: Gene symbols and Uniprot accessions.

Enter Protein IDs

Upload file to search for genes

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Filter by organism

Human

General Annotation

Search Term

Uniprot Accession

Gene Name

Description

EC Number

Synonyms

Location

Keywords

GO Terms

Family

Zinc Link

canSAR.ai Link

Similarity to Drug Targets

Nearest Drug Target

Matching Drug Targets > 50%

Matching Drug Targets > 35%

3D Structures

Only Include Homologues with Sequence Identity >=

100%

# Number of 3D Structures

# 3D Structures with Small Molecule Ligand

3D Structure Based Druggability

Only Include Homologues with Sequence Identity >=

100%

# 3D Structures with Druggability calculated

# 3D Structures predicted Druggable

% 3D Structures predicted Druggable

# 3D Structures predicted Tractable

% 3D Structures predicted Tractable

Ligand Based Druggability

Only Include Proteins with LBD Score in Top >=

100%

Ligand-based Druggability Score

Ligand-based Druggability Percentile Rank

Similarity to Protein Targets with Chemical Matter

Only Include Homologues with Sequence Identity >=

100%

Only Include Activities <=

50 nM

# Protein Variants

# Tested Compounds

# Active Compounds

# Active Ro5 Compliant Compounds (Ro5=0]

# Tested Fragments

# Active Fragments

# Active Ro5 Compliant Fragments (Ro5=0]

Genomic Alterations in Cancer

Most Prevalent Mutation

Most Prevalent CNV

Highest Expressing Cell-lines

Report Ready

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