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DESCRIPTION

Also known as IBP5_HUMAN, IGFBP5, IBP5. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Also known as IBP5_HUMAN, IGFBP5, IBP5. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell cul ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

IGFBP5

Insulin-like growth factor-binding protein 5

Evidence from Cancer Cell Lines

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RNAi (dependency score calculated by DEMETER2)

Data retrieved from DepMap at the Broad Institute .

Graph

Table

Dependencies of cell lines on IGFBP5 have been identified in the following studies

Cell Lines

Dependency >= -1

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